Risk of Ovarian Malignancy Algorithm (ROMA)
£91.00
ROMA (Risk of Ovarian Malignancy Algorithm) Blood Test in London
The Risk of Ovarian Malignancy Algorithm (ROMA) Profile (SP30) is a specialised blood test designed to assess the likelihood of ovarian malignancy in women presenting with ovarian masses or related clinical concerns. This profile measures CA 125 and HE4 tumour markers and combines the results with menopausal status to generate a ROMA score, helping to evaluate the risk of ovarian cancer and support clinical decision-making. Ideal for women undergoing investigation for ovarian abnormalities or requiring further risk assessment, this test is available at Medical Diagnosis Victoria (MDX Victoria) in London, with results typically available within 5 days.
Risk of Ovarian Malignancy Algorithm (ROMA)
This profile (SP30) is used to assess the risk of ovarian malignancy in women. CA 125 and HE4 are proteins that can be elevated in ovarian cancer, and the ROMA score combines these markers with menopausal status to estimate the likelihood of malignancy.
📊 Test Specifications
Why Choose This Test?
Symptom Investigation
This profile provides essential clarity if you are experiencing:
- Unexplained pelvic masses
- Persistent abdominal bloating or pain
- Changes in bowel or bladder habits
- Feeling full very quickly when eating
Comprehensive Biomarkers
It combines advanced protein markers with clinical algorithms:
- Cancer Antigen 125 (CA 125) analysis
- Human Epididymis Protein 4 (HE4)
- Premenopausal risk calculation (ROMA-PRE)
- Postmenopausal risk calculation (ROMA-POST)
Actionable Insights
This detailed internal view empowers patients and clinicians to:
- Support the evaluation of ovarian health thoroughly
- Assist clinicians in accurate risk assessment
- Guide optimal management and treatment planning
- Differentiate between benign and malignant possibilities
Schedule Your ROMA Profile
Map your ovarian health markers clearly. Secure an appointment with our clinical team for a rapid, gentle blood draw today.
What Is Included?
This profile provides a precise evaluation of specific protein markers and calculates risk using established clinical algorithms.
CA 125 & HE4 Proteins
Evaluates the concentration of Cancer Antigen 125 and Human Epididymis Protein 4 in the blood, which are key proteins often elevated in ovarian conditions.
Identifying elevated levels of specific tumour markers associated with ovarian tissue.
ROMA-PRE Algorithm
Calculates the specific risk index for premenopausal women by combining their CA 125 and HE4 levels into a predictive score.
Stratifying the likelihood of malignancy in women prior to menopause.
ROMA-POST Algorithm
Calculates the specific risk index for postmenopausal women to accurately assess malignancy likelihood based on their hormonal status.
Providing accurate risk assessment adjusted for postmenopausal biological changes.
Understanding the ROMA Score
The Risk of Ovarian Malignancy Algorithm (ROMA) significantly improves diagnostic accuracy compared to checking CA 125 alone. Because CA 125 can be elevated by benign conditions like endometriosis or menstruation, combining it with HE4 and factoring in your menopausal status allows clinicians to better categorise the probability of finding a malignancy, guiding faster and more appropriate referrals.
How To Read Your Laboratory Results
Your results will list your values alongside standard reference ranges and your calculated ROMA score. Important: A single out of range value or elevated score does not automatically indicate a malignancy. Results must be assessed in conjunction with your medical history, imaging, and clinical examination.
Results Timeline: Profile metrics are typically available within 5 days. Once your results are ready, they will be securely shared with you.
Need Help? Private GP Consultations
If you have questions about your diagnostic results, we offer Private GP consultations. A doctor can review your report, explain what the numbers mean for your specific situation, and discuss the best next steps or specialist referrals for managing your health.
Frequently Asked Questions
Most Searched Online Questions About Ovarian Health Risk
Related Health Categories
Ready to Check Your Ovarian Health?
Take immediate control of your diagnostic pathway today. Arrange a precise, comprehensive ROMA profile screening at our premium clinic spaces.
