Rheumatoid Profile 2

£223.00

Rheumatoid Profile II Blood Test in London

The Rheumatoid Profile II (SP29) is an advanced autoimmune and inflammatory disease screening blood test designed to investigate conditions affecting the joints, connective tissues, and immune system. Building on the Rheumatoid Profile I, this comprehensive profile includes specialised autoantibody testing to help identify autoimmune disorders such as rheumatoid arthritis, systemic lupus erythematosus (SLE), Sjögren’s syndrome, scleroderma, and other connective tissue diseases. Ideal for individuals experiencing joint pain, stiffness, swelling, fatigue, or suspected autoimmune conditions, this test provides valuable diagnostic insights. Available at Medical Diagnosis Victoria (MDX Victoria) in London, with results typically available within 10 days.

Connective Tissue & Joint Health

Rheumatoid Profile II

This profile (SP29) provides a detailed evaluation of autoimmune and inflammatory conditions, especially those affecting the joints and connective tissue. It includes all tests from Rheumatoid Profile I and adds specialized autoantibodies to help identify specific autoimmune diseases, such as systemic lupus erythematosus, Sjögren’s syndrome, and scleroderma.

📊 Test Specifications

Clinic Testing Fee

£223.00
+ £21.00 Phlebotomy Fee

🩸

Sample RequiredBlood Sample

⏱️

Turnaround Time10 Days Processing

Diagnostic Focus

Why Choose This Test?

Symptom Investigation

This advanced profile provides clarity if you are experiencing:

  • Complex or unexplained joint pain
  • Suspected connective tissue disorders
  • Systemic autoimmune flare-ups
  • Potential clotting disorder risks

Comprehensive Biomarkers

An expansive diagnostic panel combining:

  • Advanced Autoantibodies (ENA Panel & dsDNA)
  • Complement Proteins (C3 and C4)
  • Cardiolipin Antibodies (IgA, IgG, IgM)
  • Baseline inflammation markers (CRP & ESR)

Actionable Insights

This detailed internal view empowers you to:

  • Support diagnosis of SLE or Sjögren’s syndrome
  • Monitor complex connective tissue disorders
  • Evaluate active immune system consumption
  • Assess specific clotting risk factors securely

Schedule Your Rheumatoid Profile II

Map your blood, joint, and connective tissue health comprehensively. Secure an appointment with our clinical team for a rapid, gentle blood draw today.

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Component Index

What Is Included?

This expansive profile evaluates foundational health, complex autoimmune autoantibodies, immune system consumption, and coagulation risk factors.

Haematology & Inflammation

Evaluates overall blood health, cellular immune function, and baseline markers of systemic inflammation.

Full Blood Count (FBC)
White Cell Differential
C-Reactive Protein (CRP)
ESR
Uric Acid
Clinical focus:
Detecting systemic inflammation, evaluating metabolic gout risks, and establishing baseline health.

Advanced Autoimmune Panel

A detailed array of specialized autoantibodies used to identify precise connective tissue and joint disorders.

ANA
Rheumatoid Factor
dsDNA Ab
ENA Antibodies
Sm & RNP
SS-A (Ro) & SS-B (La)
Jo-1
Centromere
Histones
Clinical focus:
Pinpointing specific disorders like Lupus, Sjögren’s, scleroderma, and rheumatoid arthritis.

Immune Activity & Clotting

Measures active immune system consumption and evaluates the risk of clotting disorders linked to autoimmunity.

Complement C3
Complement C4
Cardiolipin IgA
Cardiolipin IgG
Cardiolipin IgM
Clinical focus:
Assessing disease flare activity via complement proteins and evaluating antiphospholipid risks.

Understanding Specialized Connective Tissue Markers

Building significantly on standard profiles, this comprehensive test includes the Extractable Nuclear Antigens (ENA) panel and dsDNA antibodies, which are critical for distinguishing between complex connective tissue diseases like Lupus or Sjögren’s. Furthermore, the inclusion of Complement proteins (C3 and C4) helps doctors gauge active immune system consumption during flare-ups, while cardiolipin antibodies assess potential blood clotting risks associated with these autoimmune conditions.

Pathology Reports

How To Read Your Laboratory Results

Your results will list your values alongside standard reference ranges. If a result falls outside the range, it is noted for review. Important: A single out-of-range value does not automatically indicate a medical problem. Results must be assessed in conjunction with your medical history and clinical examination.

Results Timeline: Due to the advanced nature of these assays, profile metrics are typically available within 10 days. Once your results are ready, they will be securely shared with you.

Laboratory Diagnostic Analysis

Clinical Environment Consultation

Medical Consultation

Need Help? Private GP Consultations

If you have questions about your autoimmune, ENA, or connective tissue results, we offer Private GP consultations. A doctor can review your extensive report, explain what the specialized autoantibody numbers mean, and discuss the best next steps for clinical management.

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Clinic Support

Frequently Asked Questions

Do I need to fast before the test?
No, there are no special fasting or preparation instructions required for the Rheumatoid Profile II.
How quickly will I get my results?
Due to the complex specialized autoantibody panels involved, comprehensive results will be processed and securely delivered within 10 days of sample collection.
Can I walk in, or do I need an appointment?
Walk-ins are welcome at the clinic, but booking a slot online is highly recommended to ensure priority service.
What should I do if my results are abnormal?
If your specialized autoantibodies or complement proteins are outside the reference range, we strongly recommend booking a Private GP consultation with us to review them.
Is the phlebotomy fee included in the price?
No, the £21 phlebotomy service fee is separate and payable directly at the clinic.
Will my results be sent securely?
Yes, your extensive laboratory results will be delivered securely and privately to the email address provided.
Do I need a doctor’s referral for this advanced profile?
No referral is needed. You can book this test independently to deeply investigate your connective tissue and autoimmune health.
Can I eat and drink normally before the test?
Yes, you can eat and drink normally prior to your phlebotomy appointment.
Online Trends

Most Searched Online Questions About Advanced Autoimmunity

What are ENA antibodies?
Extractable Nuclear Antigens (ENA) are a group of autoantibodies in the blood that react with proteins in the cell nucleus. They help doctors distinguish between specific connective tissue diseases.
What do Complement C3 and C4 tests measure?
Complement proteins are part of your immune system. Low levels can indicate that your immune system is highly active and consuming these proteins to drive autoimmune inflammation, such as in Lupus flare-ups.
Why test for Cardiolipin Antibodies?
Cardiolipin antibodies are often found in people with certain autoimmune conditions and can significantly increase the risk of developing abnormal blood clots in veins or arteries.
What is Systemic Lupus Erythematosus (SLE)?
SLE is a complex autoimmune disease where the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs, joints, or skin.
Can this test diagnose Sjögren’s syndrome?
This profile includes SS-A (Ro) and SS-B (La) antibodies, which are primary markers used by doctors to support a diagnosis of Sjögren’s syndrome alongside physical symptoms.

Secure Diagnostics

Ready to Check Your Joint Health?

Take immediate control of your health pathway today. Arrange a precise, comprehensive Rheumatoid Profile II screening at our premium clinic spaces.

Clinical indications listed are for general informational purposes only and do not represent a complete list of possible uses, which may vary depending on individual circumstances.

Rheumatoid Profile II results should always be assessed in conjunction with the patient’s medical history, clinical examination, and other findings by a qualified healthcare professional.