Coeliac Profile 1

£155.00

Coeliac Profile – Blood Test in London

The Coeliac Profile is a specialised blood test designed to help detect coeliac disease, an autoimmune condition triggered by gluten consumption. This comprehensive screening measures key antibodies, including tissue transglutaminase (tTG), endomysial, gliadin, and reticulin antibodies, which can indicate an immune response to gluten and support the diagnosis of coeliac disease. Ideal for individuals experiencing digestive symptoms, unexplained nutritional deficiencies, fatigue, bloating, or suspected gluten sensitivity, this test provides valuable insight into digestive and autoimmune health. Available at Medical Diagnosis Victoria (MDX Victoria) in London, with results typically available within 10 days.

Digestive & Autoimmune Health

Coeliac Profile

This profile is used to help detect coeliac disease, an autoimmune condition triggered by gluten. It measures several antibodies, including endomysial, reticulin, gliadin, and tissue transglutaminase (tTG), which can indicate an immune reaction to gluten.

📊 Test Specifications

Clinic Testing Fee

£155.00
+ £21.00 Phlebotomy Fee

🩸

Sample RequiredBlood Sample

⏱️

Turnaround Time10 Days Processing

Diagnostic Focus

Why Choose This Test?

Symptom Investigation

This profile provides essential clarity if you are experiencing:

  • Unexplained digestive discomfort
  • Suspected nutrient deficiencies
  • Chronic fatigue related to malabsorption
  • Symptoms triggered by eating gluten

Comprehensive Biomarkers

It goes beyond a basic check up by combining:

  • Tissue Transglutaminase (tTG) IgA
  • Endomysial and Reticulin IgA
  • Gliadin IgA and IgG markers
  • Total Immunoglobulin A baseline

Autoimmune Insights

This detailed internal view empowers you to:

  • Support the diagnosis of coeliac disease
  • Assess risks associated with family history
  • Differentiate between intolerances and autoimmunity
  • Take control of your diet with clear clinical data

Schedule Your Coeliac Profile

Map your autoimmune health clearly. Secure an appointment with our clinical team for a rapid, gentle blood draw today.

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Component Index

What Is Included?

This profile provides a comprehensive antibody assessment to identify immune reactions specific to coeliac disease.

Core Coeliac Markers

Evaluates primary antibodies reacting to gluten and ensures baseline immune levels are normal for accurate interpretation.

Tissue Transglutaminase IgA
Immunoglobulin A (IgA)
Clinical focus:
Detecting the most common immune response to gluten while verifying total IgA to prevent false negatives.

Advanced Antibody Screen

Assesses specific antibodies targeting connective tissues in the intestine, offering high specificity for coeliac diagnosis.

Endomysial IgA
Reticulin IgA
Clinical focus:
Confirming autoimmune reactions linked directly to intestinal lining damage characteristic of coeliac disease.

Gliadin Assessment

Measures antibodies directed against gliadin, a component of gluten, covering multiple immunoglobulin classes.

Gliadin IgA
Gliadin IgG
Clinical focus:
Broadening detection accuracy; IgG is especially vital for cases where a patient naturally has low IgA levels.

Understanding Total IgA and IgG Markers

Total Immunoglobulin A (IgA) is measured to ensure accurate interpretation of the tests. If a person is naturally deficient in total IgA, their coeliac specific IgA tests might incorrectly appear normal (a false negative). To prevent this, Gliadin IgG is included specifically to capture autoimmune activity in cases where IgA levels are low.

Pathology Reports

How To Read Your Laboratory Results

Your results will list your values alongside standard reference ranges. If an antibody level is elevated, it suggests a potential immune reaction to gluten. Elevated markers do not automatically diagnose coeliac disease on their own. Results must be assessed in conjunction with your medical history and clinical examination by a specialist.

Results Timeline: Profile metrics are typically available within 10 days. Once your results are ready, they will be securely shared with you.

Laboratory Diagnostic Analysis

Clinical Environment Consultation

Medical Consultation

Need Help? Private GP Consultations

If you have questions about your results, we offer Private GP consultations. A doctor can review your report, explain what the numbers mean for your specific digestive health, and discuss the best next steps for managing your diet and wellbeing.

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Clinic Support

Frequently Asked Questions

Do I need to fast before the test?
No, fasting is not required. However, you must maintain a normal gluten-containing diet prior to testing to ensure accurate antibody detection.
What if I have already stopped eating gluten?
If you have removed gluten from your diet, your antibody levels may have dropped, which can lead to a false negative result. Speak to a doctor about the safest way to proceed.
How quickly will I get my results?
Your comprehensive coeliac profile results will be ready within 10 days of sample collection.
What should I do if my results are positive?
If your markers suggest an autoimmune reaction, we strongly recommend booking a Private GP consultation with us to review them and discuss formal diagnostic steps.
Is the phlebotomy fee included in the price?
No, the £21 phlebotomy service fee is separate and payable directly at the clinic.
Do I need a doctor’s referral for this profile?
No referral is needed. You can book this test independently to investigate your own digestive health.
Is this test suitable for children?
Suitability may depend on age and clinical circumstances. Please contact the clinic beforehand to discuss testing a child for coeliac disease.
Online Trends

Most Searched Online Questions About Coeliac Disease

What are the symptoms of coeliac disease?
Common symptoms include abdominal pain, bloating, diarrhoea, unexplained weight loss, and chronic fatigue due to poor nutrient absorption.
What happens if I stop eating gluten before the test?
If you stop eating gluten, your body may stop producing the antibodies this profile looks for, leading to an inaccurate or false negative result.
Is coeliac disease genetic?
Yes, it strongly runs in families. If you have a first degree relative with the condition, your chances of developing it are significantly higher.
What is the difference between gluten intolerance and coeliac disease?
Coeliac disease is a severe autoimmune condition where gluten physically damages the gut lining. Gluten intolerance causes discomfort but does not trigger an autoimmune response.
What is Tissue Transglutaminase (tTG)?
It is an enzyme in the gut. In coeliac patients, the immune system mistakenly creates antibodies against this enzyme when gluten is consumed.
Why is Total IgA measured alongside other tests?
Some people naturally lack IgA antibodies. If this is not checked, the specific IgA tests for coeliac could incorrectly appear normal.

Secure Diagnostics

Ready to Check Your Digestive Health?

Take immediate control of your health pathway today. Arrange a precise, comprehensive Coeliac Profile screening at our premium clinic spaces.

Clinical indications listed are for general informational purposes only and do not represent a complete list of possible uses, which may vary depending on individual circumstances.

The results should always be assessed in conjunction with the patient’s medical history, clinical examination and other findings.